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New approach to prevent childhood caries using acid-neutralising technology

Wed. 16 July 2025

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Childhood dental caries remain a persistent public health challenge, with recent data reaffirming the need for innovative prevention strategies. Despite ongoing efforts by oral health agencies, including the Office for Health Improvement and Disparities, the goal of achieving cavity-free childhood still requires significant attention.

Dental researchers point to the dynamic balance between causative and protective factors in the caries process. Causative factors include excessive sugar consumption, poor oral hygiene, and high bacterial plaque levels. Protective strategies, meanwhile, involve the use of fluoride, improved dietary awareness, and emerging acid-neutralising technologies.

Understanding the caries process

Dental caries occur when acids produced by plaque bacteria demineralise the enamel. Fluoride plays a proven role in delaying this process and aiding remineralisation, but it does not prevent the acid production at its root.

Researchers are now focusing on technologies that neutralise these acids at the source. One such innovation uses arginine, a naturally occurring amino acid. When metabolised by certain bacteria in the mouth, arginine produces ammonia, which neutralises plaque acids. This creates a more alkaline environment that is less favourable to decay-causing bacteria and supports enamel remineralisation.

Saliva and plaque pH: a critical factor

A neutral pH in saliva maintains mineral balance, allowing fluoride and calcium to work more effectively. Acid-neutralising agents can therefore enhance fluoride's impact, reducing enamel demineralisation and promoting tooth repair. This combination has shown statistically significant reductions in caries progression in multiple clinical studies.

Sugar intake: a persistent concern

Despite public health policies like the Sugar Tax introduced in 2018, children in many regions still consume up to twice the recommended daily amount of sugar. Nearly half of that sugar comes from snacks and sugary drinks, often marketed as healthy alternatives.

Conflicting nutritional advice and a lack of awareness about hidden sugars in common children's snacks further complicate prevention. For example, dried fruits and fruit juices can contribute to acid attacks on enamel.

The role of oral health professionals

Dental professionals are critical in educating families about oral health. While information sharing is helpful, studies show that behavioural change requires consistent, tailored communication. Healthcare providers must go beyond information to reinforce good practices and dispel myths about food choices.

Moving forward with innovation

Recent studies suggest that combining fluoride with acid-neutralising compounds can significantly lower the rate of new cavity formation in children. Over a two-year period, children using such formulations experienced notably fewer caries than those using traditional fluoride toothpaste alone.

While product-specific outcomes remain proprietary to manufacturers, the science behind acid-neutralisation is gaining broader attention among oral health researchers and policymakers as a potential breakthrough in public health dentistry.

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