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Dental implants may reconnect nerves, bring back real-tooth sensation

Press Release

Sat. 14 June 2025

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Millions of people each year opt for dental implants as a reliable, long-lasting solution for missing teeth. However, traditional implants fall short of replicating the sensory functions of natural teeth. A team of researchers from Tufts University School of Dental Medicine and School of Medicine is changing that narrative by introducing a smart dental implant that could potentially restore the natural “feel” of teeth through innovative biotechnology.

Published in Scientific Reports, the groundbreaking study presents a biodegradable-coated implant that not only supports chewing and speaking more naturally but also connects with the body’s sensory system—something traditional titanium implants cannot achieve.

The science behind the sensation

Natural teeth are connected to the jawbone via periodontal ligaments filled with nerves that sense pressure, movement, and texture. Traditional implants, anchored directly into the bone, bypass this feedback mechanism. The new Tufts prototype uses a biodegradable coating containing stem cells and nerve growth proteins. As the coating dissolves, it releases these elements, encouraging the growth of nerve tissue around the implant.

“This new approach allows the implant to ‘talk’ to the brain, much like a real tooth,” says Dr. Jake Jinkun Chen, professor of periodontology and senior author of the study.

A softer surgical touch

The new implants also introduce a minimally invasive surgical technique. The smart coating includes rubbery nanofibers that work like memory foam—compressed during insertion and expanding to fit the socket gently. This method preserves surrounding nerve endings, potentially improving recovery and sensory outcomes.

Early results and what’s next

In rodent models, the implants remained stable six weeks post-surgery with no signs of inflammation. Imaging showed soft tissue integration rather than direct bone fusion—an encouraging sign for nerve regeneration.

Researchers now plan to conduct larger preclinical trials to confirm if the nerves around the implant relay signals to the brain. If successful, this could revolutionize not only dental care but also orthopedic fields such as hip replacements and bone fracture repairs.

What this means for the future of dental care

While human trials are still a few years away, this innovation highlights the future of nerve-integrated dental implants that restore both form and function. Patients may one day benefit from implants that don’t just look like natural teeth—but feel like them too.

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